• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: HOX{A6,A7,B6,B7}.p2

Z-value: 2.761

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Top targets:

Promoter	Score	Refseq	Gene	Description
chrM_+_11741	34.913		ND5	NADH dehydrogenase subunit 5
chr2_+_138104219	34.874	NM_145534	Btbd3	BTB (POZ) domain containing 3
chrM_+_2750	32.341
chrM_+_409	31.475
chrM_+_3320	30.758
chrM_+_11812	30.615
chrM_+_1550	28.216
chr3_+_136598485	27.760		Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform
chr9_-_29770699	27.515	NM_172290	Ntm	neurotrimin
chr8_+_56040211	26.508		Gpm6a	glycoprotein m6a
chr8_-_87297283	24.507		Nfix	nuclear factor I/X
chrM_+_1091	23.877
chr8_+_56040445	23.212		Gpm6a	glycoprotein m6a
chrM_+_5322	23.158		COX1	cytochrome c oxidase subunit I
chrM_+_11027	22.137
chrM_+_5398	21.006
chrM_+_5462	19.544
chrM_+_12383	18.672
chr1_+_189821727	18.447	NM_011935	Esrrg	estrogen-related receptor gamma
chr3_+_136598184	18.422		Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform
chr8_+_115093942	18.162	NM_130457	Cntnap4	contactin associated protein-like 4
chrM_+_14143	18.151
chr4_+_97248556	18.128	NM_001122952	Nfia D130039L10Rik	nuclear factor I/A RIKEN cDNA D130039L10 gene
chrM_+_13543	18.021
chr1_+_81073778	17.880	NM_172849	9430031J16Rik	RIKEN cDNA 9430031J16 gene
chr11_+_42234760	17.804		Gabrb2	gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr2_+_70312979	17.702	NM_022435	Sp5	trans-acting transcription factor 5
chr11_+_77744280	17.448	NM_021286	Sez6	seizure related gene 6
chr8_-_70342105	17.146	NM_027626	Psd3	pleckstrin and Sec7 domain containing 3
chr6_-_13789847	17.108	NM_145066	Gpr85	G protein-coupled receptor 85
chr8_+_56040193	16.612		Gpm6a	glycoprotein m6a
chr8_-_3624988	16.534	NM_001129804	Pcp2	Purkinje cell protein 2 (L7)
chr14_+_122879276	16.355		Zic2	zinc finger protein of the cerebellum 2
chr17_-_90487479	16.312		Nrxn1	neurexin I
chrM_+_3913	16.097
chr8_-_3625251	16.071	NM_008790	Pcp2	Purkinje cell protein 2 (L7)
chr15_-_8660462	16.029		Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrM_+_13320	15.721
chr2_-_79296732	15.606	NM_010894	Neurod1	neurogenic differentiation 1
chr2_+_37372112	14.767	NM_177383	Gpr21	G protein-coupled receptor 21
chr15_-_48623520	14.698	NM_001081391	Csmd3	CUB and Sushi multiple domains 3
chr10_+_90039435	14.388	NM_001177396 NM_001177398 NM_181398	Ipw Anks1b	imprinted gene in the Prader-Willi syndrome region ankyrin repeat and sterile alpha motif domain containing 1B
chrM_+_6139	14.383
chrM_+_3844	14.098
chr3_+_55586431	13.669	NM_010750	Mab21l1	mab-21-like 1 (C. elegans)
chr4_+_15808409	13.550	NM_009788	Calb1	calbindin 1
chr13_+_20564928	13.453	NM_198093	Elmo1	engulfment and cell motility 1, ced-12 homolog (C. elegans)
chrM_+_13998	13.392
chr8_+_56040553	13.348		Gpm6a	glycoprotein m6a
chrM_+_15355	13.213
chr19_+_26679649	12.942	NM_011416	Smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr6_+_79968948	12.699		Lrrtm4	leucine rich repeat transmembrane neuronal 4
chr3_+_125106995	12.675	NM_022565	Ndst4	N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr6_-_55631085	12.633		Neurod6	neurogenic differentiation 6
chr15_-_8660442	12.579		Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr13_-_16115192	12.402		B230303A05Rik	RIKEN cDNA B230303A05 gene
chr11_-_41814008	12.352	NM_008073	Gabrg2	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr2_-_7002287	12.214		Celf2	CUGBP, Elav-like family member 2
chr2_-_7002344	12.126	NM_001110229 NM_001110230 NM_001160292	Celf2	CUGBP, Elav-like family member 2
chr1_+_179374783	11.641	NM_001012330	Zfp238	zinc finger protein 238
chr12_+_30219982	11.619		Myt1l	myelin transcription factor 1-like
chr11_-_30000031	11.296		Spnb2	spectrin beta 2
chr9_-_91255831	11.257		Zic1	zinc finger protein of the cerebellum 1
chr9_+_118387306	11.130	NM_001164789 NM_010136	Eomes	eomesodermin homolog (Xenopus laevis)
chrM_+_67	11.075
chr1_-_79436564	10.986	NM_009129	Scg2	secretogranin II
chrM_+_12178	10.914
chrM_-_13886	10.494
chrX_-_161765324	10.162		Glra2	glycine receptor, alpha 2 subunit
chr2_-_6805937	10.066	NM_001110228 NM_001160293 NM_010160	Celf2	CUGBP, Elav-like family member 2
chrX_-_85360961	9.859	NM_001160403	Il1rapl1	interleukin 1 receptor accessory protein-like 1
chr10_-_63552994	9.834	NM_178678	Lrrtm3	leucine rich repeat transmembrane neuronal 3
chr18_+_69843730	9.783		Tcf4	transcription factor 4
chr15_+_91991704	9.675	NM_001159647	Cntn1	contactin 1
chr5_+_19413335	9.583	NM_001170745 NM_015823	Magi2	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr17_+_80706746	9.394	NM_001145452	Arhgef33	Rho guanine nucleotide exchange factor (GEF) 33
chr19_-_5797749	9.269		Malat1	metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr8_+_24780132	9.213	NM_177086	Zmat4	zinc finger, matrin type 4
chr11_+_29607599	9.088		Rtn4	reticulon 4
chr4_+_138012860	8.877		Camk2n1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr6_-_55631039	8.809		Neurod6	neurogenic differentiation 6
chr15_-_8660479	8.746		Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrM_+_7714	8.676		Gm10925 ATP6	predicted gene 10925 ATP synthase F0 subunit 6
chr18_+_23468585	8.521		Dtna	dystrobrevin alpha
chr1_+_145487825	8.514	NM_020025	B3galt2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr5_+_13125413	8.423		LOC100503462	hypothetical LOC100503462
chr2_+_61884596	8.325	NM_033552	Slc4a10	solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr3_+_17954324	8.221	NM_021560	Bhlhe22	basic helix-loop-helix family, member e22
chr13_-_84204320	8.018		LOC553095	hypothetical LOC553095
chr5_+_107926763	7.960	NM_001007574 NM_001168557	A830010M20Rik	RIKEN cDNA A830010M20 gene
chr2_+_61642509	7.957	NM_009322	Tbr1	T-box brain gene 1
chr11_-_79317471	7.760		Omg	oligodendrocyte myelin glycoprotein
chr4_+_101180580	7.720	NM_001164584 NM_001164585	Dnajc6	DnaJ (Hsp40) homolog, subfamily C, member 6
chr3_+_13946371	7.610	NM_001163329 NM_001163330	Ralyl	RALY RNA binding protein-like
chr14_-_122138082	7.589	NM_001128307 NM_001128308	Dock9	dedicator of cytokinesis 9
chr9_-_58049765	7.577		Islr2	immunoglobulin superfamily containing leucine-rich repeat 2
chr4_-_82151180	7.556	NM_001113209 NM_001113210 NM_008687	Nfib	nuclear factor I/B
chr3_-_151856766	7.470	NM_025926	Dnajb4	DnaJ (Hsp40) homolog, subfamily B, member 4
chr1_-_160286359	7.398	NM_207583	Fam5b	family with sequence similarity 5, member B
chr3_-_143865162	7.356	NM_001161770 NM_001161769	Lmo4	LIM domain only 4
chr11_+_117623703	7.312		Tnrc6c	trinucleotide repeat containing 6C
chr3_-_80606500	7.305		Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr11_-_33893151	7.214	NM_001190886	Kcnip1	Kv channel-interacting protein 1
chr3_+_17954500	7.197		Bhlhe22	basic helix-loop-helix family, member e22
chr10_+_101621491	6.988	NM_001162368	Mgat4c 4930402I19Rik	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative) RIKEN cDNA 4930402I19 gene
chr4_+_101180625	6.987		Dnajc6	DnaJ (Hsp40) homolog, subfamily C, member 6
chr7_+_97535490	6.889	NM_001040087 NM_001040088	Sytl2	synaptotagmin-like 2
chr8_-_47292863	6.821
chr2_+_174171943	6.755
chr8_+_119984482	6.732		4933407C03Rik	RIKEN cDNA 4933407C03 gene
chr17_-_90436488	6.682		Nrxn1	neurexin I
chr15_+_22966203	6.538	NM_001081299	Cdh18	cadherin 18
chr3_-_80606641	6.516		Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr4_-_82151657	6.451		Nfib	nuclear factor I/B
chr17_+_70871444	6.407	NM_001128180	Dlgap1	discs, large (Drosophila) homolog-associated protein 1
chr13_+_83663817	6.294		Mef2c	myocyte enhancer factor 2C
chr12_+_110783786	6.238		Meg3	maternally expressed 3
chr7_+_134094045	6.200	NM_144926	Sez6l2	seizure related 6 homolog like 2
chr4_-_63707964	6.145		Tnc	tenascin C
chr6_-_87793459	6.018		Cnbp	cellular nucleic acid binding protein
chr9_+_37175190	5.969	NM_175189	Hepacam	hepatocyte cell adhesion molecule
chr11_-_41813792	5.914	NM_177408	Gabrg2	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr2_+_109739389	5.741		Lin7c	lin-7 homolog C (C. elegans)
chr15_-_8660729	5.681	NM_148938	Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_-_30168153	5.678		Spnb2	spectrin beta 2
chr14_+_61757271	5.654	NM_172809	Sacs	sacsin
chr8_-_47292973	5.568		Slc25a4	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr4_-_35792385	5.463	NM_001166001 NM_175516	Lingo2	leucine rich repeat and Ig domain containing 2
chr15_-_81222718	5.450		St13	suppression of tumorigenicity 13
chr1_+_66368571	5.450		Mtap2	microtubule-associated protein 2
chr4_+_104829963	5.410		Ppap2b	phosphatidic acid phosphatase type 2B
chr9_+_113721698	5.399	NM_001081960 NM_029633	Clasp2	CLIP associating protein 2
chr7_+_98239427	5.380		Dlg2	discs, large homolog 2 (Drosophila)
chr7_-_29678773	5.377		Actn4	actinin alpha 4
chr11_-_41995688	5.229		Gabra1	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr18_+_69753035	5.225		Tcf4	transcription factor 4
chr13_-_29045399	5.198	NM_009238	Sox4	SRY-box containing gene 4
chr2_+_65458814	5.152
chr2_-_77541328	5.138	NM_001113399	Zfp385b	zinc finger protein 385B
chrM_-_622	5.116
chr13_-_105844882	5.109	NM_029879	Rgs7bp	regulator of G-protein signalling 7 binding protein
chr3_-_146433544	5.096	NM_001164199	Prkacb	protein kinase, cAMP dependent, catalytic, beta
chr18_+_23468655	5.055		Dtna	dystrobrevin alpha
chr8_+_56122680	5.024		Gpm6a	glycoprotein m6a
chr14_+_66963139	5.024	NM_019675	Stmn4	stathmin-like 4
chr9_+_34296315	5.010	NM_001190911 NM_001190912 NM_001190913 NM_001190914 NM_026324	Kirrel3	kin of IRRE like 3 (Drosophila)
chr9_-_40153864	4.989		Gramd1b	GRAM domain containing 1B
chr8_-_89996089	4.974		Cbln1	cerebellin 1 precursor protein
chr8_+_96335202	4.963		Gnao1	guanine nucleotide binding protein, alpha O
chr15_-_37389073	4.952	NM_001170867 NM_001170868	Ncald	neurocalcin delta
chr14_+_14286471	4.950	NM_001163032	Synpr	synaptoporin
chr10_+_69487700	4.897		Ank3	ankyrin 3, epithelial
chr5_-_124053691	4.897		Clip1	CAP-GLY domain containing linker protein 1
chr2_+_70400179	4.887	NM_008077	Gad1	glutamic acid decarboxylase 1
chr6_-_138371302	4.884		Lmo3	LIM domain only 3
chr19_+_8665743	4.883	NM_001164634 NM_031194	Slc22a8	solute carrier family 22 (organic anion transporter), member 8
chr10_+_96942181	4.878		Dcn	decorin
chr19_+_4711220	4.821	NM_021287	Spnb3	spectrin beta 3
chr6_+_53523365	4.787	NM_172728	Creb5	cAMP responsive element binding protein 5
chr15_-_8660393	4.716		Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_-_84265422	4.706	NM_018782	Calcrl	calcitonin receptor-like
chrX_-_163645313	4.695		Tmsb4x	thymosin, beta 4, X chromosome
chr11_-_33103458	4.692	NM_019916	Tlx3	T-cell leukemia, homeobox 3
chr11_-_51414597	4.654		Hnrnpab	heterogeneous nuclear ribonucleoprotein A/B
chr16_-_42340613	4.642	NM_008083	Gap43	growth associated protein 43
chr2_-_42508486	4.606		Lrp1b	low density lipoprotein-related protein 1B (deleted in tumors)
chr16_-_88290458	4.589	NM_010348 NM_146072	Grik1	glutamate receptor, ionotropic, kainate 1
chr12_+_110800212	4.582		Meg3	maternally expressed 3
chr2_-_170232008	4.570		Bcas1	breast carcinoma amplified sequence 1
chr7_+_62090867	4.562		Luzp2	leucine zipper protein 2
chr9_-_52484889	4.560		AI593442	expressed sequence AI593442
chr6_+_104443037	4.536	NM_017383	Cntn6	contactin 6
chr2_+_21289168	4.534	NM_001004761	Gpr158	G protein-coupled receptor 158
chr4_+_97444494	4.510		Nfia	nuclear factor I/A
chr1_-_166368439	4.503		Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide
chr12_+_30213224	4.499	NM_001093775 NM_001093778 NM_008666	Myt1l	myelin transcription factor 1-like
chr19_-_5797068	4.455
chrM_+_9875	4.452		ND4L	NADH dehydrogenase subunit 4L
chr3_+_28162135	4.450	NM_001163007 NM_001163008 NM_001163009 NM_026910	Tnik	TRAF2 and NCK interacting kinase
chr12_-_84828657	4.445	NM_058212	Dpf3	D4, zinc and double PHD fingers, family 3
chr3_-_80606598	4.432		Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr1_-_64167952	4.384	NM_033563	Klf7	Kruppel-like factor 7 (ubiquitous)
chr11_-_42134548	4.364	NM_001099641 NM_008068	Gabra6	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6
chr19_+_4711207	4.336		Spnb3	spectrin beta 3
chr4_+_101927543	4.259	NM_019840	Pde4b	phosphodiesterase 4B, cAMP specific
chr9_-_58050091	4.238	NM_001161536 NM_177193 NM_001161539	Islr2	immunoglobulin superfamily containing leucine-rich repeat 2
chrM_+_9458	4.220		ND3	NADH dehydrogenase subunit 3
chr5_-_122907269	4.165		Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr10_-_108447894	4.110		Syt1	synaptotagmin I
chr9_+_120868808	4.075		Ctnnb1	catenin (cadherin associated protein), beta 1
chr11_+_94871643	4.049		Samd14	sterile alpha motif domain containing 14
chr3_-_151856716	4.047		Dnajb4	DnaJ (Hsp40) homolog, subfamily B, member 4
chr16_+_7409879	4.038		Rbfox1	RNA binding protein, fox-1 homolog (C. elegans) 1
chr1_+_148342795	4.035	NM_153539	Fam5c	family with sequence similarity 5, member C
chr5_+_72091188	4.017	NM_008069	Gabrb1	gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
chr8_-_89996474	3.989	NM_019626	Cbln1	cerebellin 1 precursor protein
chr9_-_58049842	3.987		Islr2	immunoglobulin superfamily containing leucine-rich repeat 2
chr18_-_31606908	3.986	NM_009308	Syt4	synaptotagmin IV
chr1_-_156731538	3.983		Cacna1e	calcium channel, voltage-dependent, R type, alpha 1E subunit
chr12_+_101444303	3.959		Calm1	calmodulin 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
3.59	3.16e-22	GO:0007399	nervous system development
4.10	2.77e-20	GO:0022008	neurogenesis
2.52	1.21e-19	GO:0048731	system development
4.12	5.10e-19	GO:0048699	generation of neurons
2.35	5.29e-18	GO:0048856	anatomical structure development
1.56	5.99e-15	GO:0050794	regulation of cellular process
2.15	7.35e-15	GO:0007275	multicellular organismal development
2.08	8.91e-15	GO:0032502	developmental process
2.46	5.18e-14	GO:0030154	cell differentiation
2.41	1.26e-13	GO:0048869	cellular developmental process
1.48	2.29e-13	GO:0065007	biological regulation
1.49	1.10e-12	GO:0050789	regulation of biological process
5.12	2.36e-11	GO:0000904	cell morphogenesis involved in differentiation
4.88	3.70e-11	GO:0019226	transmission of nerve impulse
4.88	3.70e-11	GO:0035637	multicellular organismal signaling
6.04	3.80e-11	GO:0007409	axonogenesis
2.56	4.21e-11	GO:0051239	regulation of multicellular organismal process
2.63	5.43e-11	GO:0009653	anatomical structure morphogenesis
5.70	5.86e-11	GO:0048667	cell morphogenesis involved in neuron differentiation
4.25	9.42e-11	GO:0000902	cell morphogenesis
5.45	1.90e-10	GO:0048812	neuron projection morphogenesis
2.07	3.45e-10	GO:0048522	positive regulation of cellular process
3.10	3.91e-10	GO:0048468	cell development
3.77	4.83e-10	GO:0030182	neuron differentiation
3.90	1.32e-09	GO:0032989	cellular component morphogenesis
4.55	3.52e-09	GO:0031175	neuron projection development
4.06	3.64e-09	GO:0048666	neuron development
4.28	3.66e-09	GO:0051960	regulation of nervous system development
4.67	4.22e-09	GO:0048858	cell projection morphogenesis
3.33	4.59e-09	GO:0007154	cell communication
2.04	5.79e-09	GO:0048519	negative regulation of biological process
2.75	5.99e-09	GO:0032879	regulation of localization
4.07	6.84e-09	GO:0044057	regulation of system process
4.58	6.99e-09	GO:0032990	cell part morphogenesis
2.99	7.00e-09	GO:0051128	regulation of cellular component organization
2.23	1.07e-08	GO:0065008	regulation of biological quality
1.91	1.87e-08	GO:0048518	positive regulation of biological process
4.35	2.53e-08	GO:0050767	regulation of neurogenesis
3.97	2.79e-08	GO:0060284	regulation of cell development
1.82	3.73e-08	GO:0051179	localization
4.72	4.19e-08	GO:0045664	regulation of neuron differentiation
3.87	5.49e-08	GO:0007267	cell-cell signaling
2.03	9.98e-08	GO:0048523	negative regulation of cellular process
4.99	1.66e-07	GO:0031644	regulation of neurological system process
1.83	4.02e-07	GO:0016043	cellular component organization
4.54	5.31e-07	GO:0007268	synaptic transmission
2.72	5.58e-07	GO:2000026	regulation of multicellular organismal development
3.10	6.83e-07	GO:0007155	cell adhesion
3.14	8.24e-07	GO:0040011	locomotion
3.07	8.72e-07	GO:0022610	biological adhesion
2.25	9.11e-07	GO:0023051	regulation of signaling
2.84	1.27e-06	GO:0051049	regulation of transport
2.50	1.77e-06	GO:0050793	regulation of developmental process
1.54	3.20e-06	GO:0032501	multicellular organismal process
3.30	3.38e-06	GO:0030030	cell projection organization
2.73	4.27e-06	GO:0045595	regulation of cell differentiation
1.75	4.82e-06	GO:0071840	cellular component organization or biogenesis
2.03	8.82e-06	GO:0048513	organ development
3.57	1.06e-05	GO:0007610	behavior
6.04	1.47e-05	GO:0007411	axon guidance
1.63	3.23e-05	GO:0031323	regulation of cellular metabolic process
1.75	3.85e-05	GO:0051234	establishment of localization
1.54	6.47e-05	GO:0023052	signaling
1.74	7.06e-05	GO:0006810	transport
1.63	8.26e-05	GO:0060255	regulation of macromolecule metabolic process
9.75	8.89e-05	GO:0050806	positive regulation of synaptic transmission
4.30	1.71e-04	GO:0051969	regulation of transmission of nerve impulse
9.00	1.99e-04	GO:0051971	positive regulation of transmission of nerve impulse
1.21	2.28e-04	GO:0009987	cellular process
3.86	2.36e-04	GO:0006935	chemotaxis
3.86	2.36e-04	GO:0042330	taxis
3.09	2.40e-04	GO:0007417	central nervous system development
10.27	2.57e-04	GO:0043242	negative regulation of protein complex disassembly
4.39	2.70e-04	GO:0050804	regulation of synaptic transmission
1.80	3.55e-04	GO:0071842	cellular component organization at cellular level
8.36	4.16e-04	GO:0031646	positive regulation of neurological system process
3.46	4.22e-04	GO:0051270	regulation of cellular component movement
2.24	4.38e-04	GO:0051641	cellular localization
1.53	4.54e-04	GO:0019222	regulation of metabolic process
3.56	4.70e-04	GO:0033043	regulation of organelle organization
6.46	5.08e-04	GO:0001508	regulation of action potential
3.99	5.50e-04	GO:0051129	negative regulation of cellular component organization
2.38	6.10e-04	GO:0010628	positive regulation of gene expression
2.77	8.62e-04	GO:0051094	positive regulation of developmental process
4.43	1.15e-03	GO:0051493	regulation of cytoskeleton organization
2.40	1.40e-03	GO:0045893	positive regulation of transcription, DNA-dependent
8.43	1.55e-03	GO:0033555	multicellular organismal response to stress
8.43	1.55e-03	GO:0043244	regulation of protein complex disassembly
1.85	1.59e-03	GO:0042221	response to chemical stimulus
1.54	1.66e-03	GO:0080090	regulation of primary metabolic process
2.57	1.86e-03	GO:0048878	chemical homeostasis
2.36	2.00e-03	GO:0051254	positive regulation of RNA metabolic process
6.99	2.35e-03	GO:0051494	negative regulation of cytoskeleton organization
1.71	2.72e-03	GO:0071841	cellular component organization or biogenesis at cellular level
3.19	3.05e-03	GO:0051046	regulation of secretion
1.87	3.26e-03	GO:0048583	regulation of response to stimulus
3.53	3.50e-03	GO:0061061	muscle structure development
2.58	3.67e-03	GO:0009605	response to external stimulus
2.09	3.92e-03	GO:0010646	regulation of cell communication
7.52	4.18e-03	GO:0050808	synapse organization
3.12	4.33e-03	GO:0007420	brain development
3.09	5.01e-03	GO:0051130	positive regulation of cellular component organization
3.31	5.12e-03	GO:0030334	regulation of cell migration
2.27	5.25e-03	GO:0006811	ion transport
1.96	5.36e-03	GO:0010604	positive regulation of macromolecule metabolic process
2.21	5.48e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.66	6.14e-03	GO:0051252	regulation of RNA metabolic process
4.13	6.14e-03	GO:0042391	regulation of membrane potential
3.26	6.33e-03	GO:2000145	regulation of cell motility
2.19	6.88e-03	GO:0042592	homeostatic process
4.34	7.24e-03	GO:0042692	muscle cell differentiation
3.12	7.29e-03	GO:0040012	regulation of locomotion
18.00	7.69e-03	GO:0021781	glial cell fate commitment
1.59	8.57e-03	GO:0051171	regulation of nitrogen compound metabolic process
1.60	9.21e-03	GO:0010468	regulation of gene expression
2.15	9.88e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.59	1.02e-02	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.04	1.25e-02	GO:0035556	intracellular signal transduction
3.64	1.52e-02	GO:0044087	regulation of cellular component biogenesis
5.71	1.52e-02	GO:0032271	regulation of protein polymerization
2.15	1.70e-02	GO:0051649	establishment of localization in cell
8.86	1.81e-02	GO:0031110	regulation of microtubule polymerization or depolymerization
7.34	1.83e-02	GO:0042552	myelination
2.12	1.84e-02	GO:0010557	positive regulation of macromolecule biosynthetic process
1.63	1.90e-02	GO:0006355	regulation of transcription, DNA-dependent
2.33	2.04e-02	GO:0019220	regulation of phosphate metabolic process
2.33	2.04e-02	GO:0051174	regulation of phosphorus metabolic process
1.59	2.06e-02	GO:2000112	regulation of cellular macromolecule biosynthetic process
7.20	2.12e-02	GO:0045665	negative regulation of neuron differentiation
2.91	2.14e-02	GO:0022603	regulation of anatomical structure morphogenesis
2.80	2.44e-02	GO:0090066	regulation of anatomical structure size
1.84	2.45e-02	GO:0009893	positive regulation of metabolic process
7.07	2.45e-02	GO:0007272	ensheathment of neurons
7.07	2.45e-02	GO:0008366	axon ensheathment
1.92	2.69e-02	GO:0009966	regulation of signal transduction
4.42	2.86e-02	GO:0007611	learning or memory
10.40	2.94e-02	GO:0051930	regulation of sensory perception of pain
10.40	2.94e-02	GO:0051931	regulation of sensory perception
6.81	3.24e-02	GO:0070507	regulation of microtubule cytoskeleton organization
13.77	3.45e-02	GO:0007026	negative regulation of microtubule depolymerization
13.77	3.45e-02	GO:0034394	protein localization at cell surface
1.32	3.57e-02	GO:0050896	response to stimulus
4.32	3.62e-02	GO:0043254	regulation of protein complex assembly
5.77	3.89e-02	GO:0019228	regulation of action potential in neuron
2.02	4.01e-02	GO:0031328	positive regulation of cellular biosynthetic process
1.54	4.12e-02	GO:0031326	regulation of cellular biosynthetic process
4.60	4.44e-02	GO:0010639	negative regulation of organelle organization
9.68	4.55e-02	GO:0014015	positive regulation of gliogenesis
5.03	4.67e-02	GO:0042063	gliogenesis
13.00	4.69e-02	GO:0031114	regulation of microtubule depolymerization

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
2.13	1.09e-20	GO:0071944	cell periphery
2.09	6.84e-19	GO:0005886	plasma membrane
4.71	8.37e-17	GO:0045202	synapse
4.30	3.06e-16	GO:0043005	neuron projection
5.09	6.75e-13	GO:0043025	neuronal cell body
5.58	2.17e-12	GO:0030424	axon
4.85	2.97e-12	GO:0044297	cell body
2.80	2.54e-11	GO:0042995	cell projection
1.20	5.36e-11	GO:0005623	cell
1.20	5.36e-11	GO:0044464	cell part
2.22	9.71e-10	GO:0044459	plasma membrane part
2.73	1.23e-08	GO:0005626	insoluble fraction
4.44	2.71e-08	GO:0030425	dendrite
4.08	4.13e-08	GO:0044456	synapse part
5.82	6.43e-08	GO:0045211	postsynaptic membrane
2.39	1.66e-07	GO:0000267	cell fraction
2.99	2.94e-07	GO:0030054	cell junction
2.53	1.97e-06	GO:0005624	membrane fraction
1.33	1.11e-05	GO:0016020	membrane
1.22	1.68e-04	GO:0005622	intracellular
2.97	2.19e-04	GO:0044463	cell projection part
4.82	3.29e-04	GO:0019717	synaptosome
3.30	4.80e-04	GO:0048471	perinuclear region of cytoplasm
1.22	5.73e-04	GO:0044424	intracellular part
4.61	1.29e-03	GO:0033267	axon part
1.85	1.84e-03	GO:0005856	cytoskeleton
1.25	7.13e-03	GO:0005737	cytoplasm
1.53	8.60e-03	GO:0043234	protein complex
1.22	8.98e-03	GO:0043226	organelle
2.00	1.06e-02	GO:0044430	cytoskeletal part
1.21	1.61e-02	GO:0043229	intracellular organelle
3.80	2.05e-02	GO:0005938	cell cortex
6.55	2.18e-02	GO:0034707	chloride channel complex
8.02	2.20e-02	GO:0030666	endocytic vesicle membrane
28.08	2.35e-02	GO:0008091	spectrin
1.34	2.37e-02	GO:0005634	nucleus
6.07	3.59e-02	GO:0030665	clathrin coated vesicle membrane
2.13	3.78e-02	GO:0005887	integral to plasma membrane
1.69	3.83e-02	GO:0005829	cytosol
1.26	4.02e-02	GO:0044425	membrane part
7.02	4.76e-02	GO:0042734	presynaptic membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.88	1.88e-23	GO:0005515	protein binding
1.35	6.88e-12	GO:0005488	binding
3.87	1.20e-05	GO:0022836	gated channel activity
2.56	1.98e-05	GO:0001071	nucleic acid binding transcription factor activity
2.56	1.98e-05	GO:0003700	sequence-specific DNA binding transcription factor activity
2.92	2.46e-05	GO:0019904	protein domain specific binding
2.29	2.91e-05	GO:0005102	receptor binding
8.05	3.42e-05	GO:0005230	extracellular ligand-gated ion channel activity
3.41	6.86e-05	GO:0016563	transcription activator activity
3.14	1.78e-04	GO:0022838	substrate-specific channel activity
3.04	3.18e-04	GO:0015267	channel activity
2.24	3.30e-04	GO:0030528	transcription regulator activity
3.03	3.34e-04	GO:0022803	passive transmembrane transporter activity
3.08	4.22e-04	GO:0005216	ion channel activity
15.60	4.71e-04	GO:0004890	GABA-A receptor activity
2.45	5.46e-04	GO:0015075	ion transmembrane transporter activity
2.68	5.74e-04	GO:0008092	cytoskeletal protein binding
4.95	8.03e-04	GO:0005516	calmodulin binding
3.04	8.62e-04	GO:0032403	protein complex binding
5.25	1.05e-03	GO:0015276	ligand-gated ion channel activity
5.25	1.05e-03	GO:0022834	ligand-gated channel activity
13.37	1.30e-03	GO:0016917	GABA receptor activity
2.16	2.52e-03	GO:0019899	enzyme binding
3.12	2.67e-03	GO:0019900	kinase binding
2.19	4.43e-03	GO:0022891	substrate-specific transmembrane transporter activity
1.98	5.63e-03	GO:0005215	transporter activity
2.29	5.87e-03	GO:0043565	sequence-specific DNA binding
5.77	8.46e-03	GO:0005253	anion channel activity
3.17	1.04e-02	GO:0019901	protein kinase binding
2.17	1.32e-02	GO:0046983	protein dimerization activity
4.10	1.33e-02	GO:0008509	anion transmembrane transporter activity
2.02	1.46e-02	GO:0022892	substrate-specific transporter activity
2.04	1.57e-02	GO:0022857	transmembrane transporter activity
11.70	1.78e-02	GO:0035255	ionotropic glutamate receptor binding
5.67	2.71e-02	GO:0005254	chloride channel activity
15.60	3.06e-02	GO:0051010	microtubule plus-end binding
9.75	4.55e-02	GO:0043548	phosphatidylinositol 3-kinase binding